The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 30, 2013

Filed:

Jul. 30, 2010
Applicants:

François Voelker, Montrond les Bains, FR;

Laurence Dumon-seignovert, Pont du Chateau, FR;

Philippe Soucaille, Deyme, FR;

Inventors:

François Voelker, Montrond les Bains, FR;

Laurence Dumon-Seignovert, Pont du Chateau, FR;

Philippe Soucaille, Deyme, FR;

Assignee:

Metabolic Explorer, Saint Beauzire, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 7/56 (2006.01); C12P 7/18 (2006.01); C07H 21/04 (2006.01); C12N 1/00 (2006.01); C12N 1/21 (2006.01); C12N 1/19 (2006.01); C12N 9/88 (2006.01); C12P 7/26 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention concerns a method for the production of a biochemical selected among lactic acid, acetol and 1,2-propanediol, comprising culturing a microorganism modified for an improved production of the biochemical selected among lactic acid, acetol and 1,2-propanediol in an appropriate culture medium and recovery of the desired biochemical which may be further purified wherein the microorganism expresses a methylglyoxal synthase (MGS) enzyme which activity is not inhibited by orthophosphate. The present invention concerns a mutant methylglyoxal synthase (MGS) comprising at least one amino acid residue in the protein sequence of the parent enzyme replaced by a different amino acid residue at the same position wherein


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