The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2013
Filed:
Mar. 10, 2008
Applicants:
Thomas Van Der Does, Wilnis, NL;
Harold Monro Moody, Gulpen, NL;
Theodorus Johannes Godfried Maria Van Dooren, Roermond, NL;
Inventors:
Thomas Van Der Does, Wilnis, NL;
Harold Monro Moody, Gulpen, NL;
Theodorus Johannes Godfried Maria Van Dooren, Roermond, NL;
Assignee:
DSM Sinochem Pharmaceuticals Netherlands B.V., Delft, NL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention describes a process for the synthesis of a semi-synthetic β-lactam compound from a nucleus and a side chain selected from the group consisting of D-phenylglycine and D-dihydro-phenylglycine in the form of a side chain ester and an enzyme catalyzing the coupling of the side chain ester to the nucleus characterized in that the side chain ester is not isolated as a solid intermediate.