The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2013
Filed:
Jul. 12, 2009
Birgit Baumgarten, Riehen, CH;
Francois Gessier, Altkirch, FR;
Andreas Katopodis, Bottinmingen, CH;
Richard Knochenmuss, Birmensdorf, CH;
Rocco Falchetto, Biubiasco, CH;
Silvio Roggo, Nuttenz, CH;
Andreas Sailer, Schopfham, DE;
Klaus Seuwen, Michelbach-le-Bas, FR;
Carsten Spanka, Loerrach, DE;
Juan Zhang, Zurich, CH;
Sebastien Hannedouche, Namue, BG;
Sophie Noel, Welcourt, BG;
Marie-odile Roy, Brussels, BG;
Yu Chen, La Jolla, CA (US);
Charles Y. Cho, San Diego, CA (US);
Wei LI, San Diego, CA (US);
Weijun Shen, San Diego, CA (US);
Birgit Baumgarten, Riehen, CH;
Francois Gessier, Altkirch, FR;
Andreas Katopodis, Bottinmingen, CH;
Richard Knochenmuss, Birmensdorf, CH;
Rocco Falchetto, Biubiasco, CH;
Silvio Roggo, Nuttenz, CH;
Andreas Sailer, Schopfham, DE;
Klaus Seuwen, Michelbach-le-Bas, FR;
Carsten Spanka, Loerrach, DE;
Juan Zhang, Zurich, CH;
Sebastien Hannedouche, Namue, BG;
Sophie Noel, Welcourt, BG;
Marie-Odile Roy, Brussels, BG;
Yu Chen, La Jolla, CA (US);
Charles Y. Cho, San Diego, CA (US);
Wei Li, San Diego, CA (US);
Weijun Shen, San Diego, CA (US);
Novartis AG, Basel, CH;
IRM LLC, Hamilton, BM;
Euroscreen SA, Gosselies, BE;
The Scripps Research Institute, La Jolla, CA (US);
Abstract
The present invention relates to modulators of the interaction between Epstein-Barr Virus induced receptor-2 (EBi2) and cholest-5-ene-3b,7b,25-triol (7,25-dihydroxycholesterol) ('7,25DHC') and/or cholest-5-ene-3b, 7b-diol (7-hydroxycholesterol) ('7HC'). The modulator maybe a small chemical molecule, antibody or other therapeutic protein. Methods of medical treatment and methods of identifying modulators are also described.