The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 30, 2013
Filed:
May. 15, 2003
Keelung Hong, San Francisco, CA (US);
Wei-wen Zheng, Las Vegas, NV (US);
Daryl C. Drummond, Concord, CA (US);
Dmitri B. Kirpotin, San Francisco, CA (US);
Mark Eamon Hayes, San Francisco, CA (US);
Keelung Hong, San Francisco, CA (US);
Wei-Wen Zheng, Las Vegas, NV (US);
Daryl C. Drummond, Concord, CA (US);
Dmitri B. Kirpotin, San Francisco, CA (US);
Mark Eamon Hayes, San Francisco, CA (US);
Sutter West Bay Hospital, San Francisco, CA (US);
Abstract
A process for preparing a microparticulate complex is provided. The process comprises (a) combining a particle-forming component ('PFC') and a nucleic acid-like component ('NAC') in a monophasic composition comprising water and a water-miscible, organic solvent to form a mixture wherein the PFC and the NAC are independently molecularly or micellarly soluble in the aqueous/organic solvent system, and (b) reducing the amount of the organic solvent in the mixture. This effects formation of the microparticulate complex of the NAC and the PFC. Also provided is a microparticulate complex that comprises a particle-forming component complexed to a nucleic acid-like component forming an approximately spherical particle, wherein the particle-forming component encloses an interior of the particle containing the nucleic acid-like component and the so-enclosed interior volume has less than about 50% (preferably less than 20%) of the volume containing free water.