The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2013

Filed:

Jul. 09, 2012
Applicants:

Clinton Alawn Krueger, Milton, MA (US);

Ching Wu, Acton, MA (US);

Christopher K Hilton, Acton, MA (US);

Inventors:

Clinton Alawn Krueger, Milton, MA (US);

Ching Wu, Acton, MA (US);

Christopher K Hilton, Acton, MA (US);

Assignee:

Excellims Corporation, Acton, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 59/44 (2006.01); G01N 27/64 (2006.01); H01J 49/34 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention describes a method and apparatus for separating chemical and/or biological samples based on selective ion-molecular interactions in the gas phase. A chemical modifier is added to the drift gas that interacts selectively with a targeted molecule in at least one component of the sample in a drift tube. The component may be impurities and/or interferences in the sample whereby the chemical modifier enhances sample resolution by shifting the components drift times. In addition, reagents can be added to the sample prior to, during, or after ionization to form a complex with selected components in the sample. In addition, one or more internal and/or external standard can also be added to the sample as a calibration for the measurement.


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