The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2013
Filed:
Apr. 20, 2011
Elaine S E Stokes, Macclesfield, GB;
Darren Mckerrecher, Macclesfield, GB;
Laurent F a Hennequin, Reims, FR;
Patrick Ple, Reims, FR;
Elaine S E Stokes, Macclesfield, GB;
Darren Mckerrecher, Macclesfield, GB;
Laurent F A Hennequin, Reims, FR;
Patrick Ple, Reims, FR;
AstraZeneca AB, Sodertalje, SE;
Abstract
The invention relates to the use of compounds of formula (I) and salts thereof, in the manufacture of a medicament for use in the production of an antiangiogenic and/or vascular permeability reducing effect in warm-blooded animals, processes for the preparation of such compounds, pharmaceutical compositions containing a compound of formula I or a pharmaceutically acceptable salt thereof as active ingredient and compounds of formula I. The compounds of formula I and the pharmaceutically acceptable salts thereof inhibit the effects of VEGF, a property of value in the treatment of a number of disease states including cancer and rheumatoid arthritis.