The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8492427 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 23, 2013

Filed:

Jul. 01, 2009
Applicants:

Emanuela Gancia, Harlow Essex, GB;

Robert Andrew Heald, Harlow Essex, GB;

Philip Jackson, Harlow Essex, GB;

Stephen Price, Harlow Essex, GB;

Inventors:

Emanuela Gancia, Harlow Essex, GB;

Robert Andrew Heald, Harlow Essex, GB;

Philip Jackson, Harlow Essex, GB;

Stephen Price, Harlow Essex, GB;

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/437 (2006.01); A61K 31/4035 (2006.01); A61K 31/416 (2006.01); A61K 31/4985 (2006.01); C07D 231/54 (2006.01); C07D 241/00 (2006.01); C07D 221/00 (2006.01); C07D 209/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention relates to isoindolones of formula, (I) with anti-cancer and/or anti-inflammatory activity and more specifically with MEK kinase inhibitory activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth, treating a hyperproliferative disorder, or treating an inflammatory disease in a mammal. The invention also relates to methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.


Find Patent Forward Citations

Gancia, Emanuela. (2013). Isoindolones derivatives as mek kinase inhibitors and methods of use (U.S. Patent No. 8492427). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8492427

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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