The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2013

Filed:

Mar. 12, 2010
Applicants:

Hayley Binch, Encinitas, CA (US);

Masaya Hashimoto, Tsukuba, JP;

Toshiharu Iwama, Tsukuba, JP;

Nobuhiko Kawanishi, Moriya, JP;

Michael Mortimore, Abington, GB;

Mitsuru Ohkubo, Ushiku, JP;

Tomoko Sunami, Tokai-mura, JP;

Inventors:

Hayley Binch, Encinitas, CA (US);

Masaya Hashimoto, Tsukuba, JP;

Toshiharu Iwama, Tsukuba, JP;

Nobuhiko Kawanishi, Moriya, JP;

Michael Mortimore, Abington, GB;

Mitsuru Ohkubo, Ushiku, JP;

Tomoko Sunami, Tokai-mura, JP;

Assignees:

Vertex Pharmaceuticals Incorporated, Cambridge, MA (US);

MSD K.K., Chiyoda-Ku, Tokyo, JP;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 403/14 (2006.01); A61K 31/535 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a compound of Formula (I): wherein Ris H or Calkyl; Ris H or Calkyl; Rand Rare each independently H or Calkyl, where the alkyl may be substituted with one to three of the same or different substituents selected from R; Ris H, hydroxy, Calkyl, or OCH; and Ris F or Cl, or a pharmaceutically acceptable salt or ester thereof.


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