The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2013

Filed:

Jun. 24, 2011
Applicants:

Ekambar Kandimalla, Southborough, MA (US);

Tao Lan, Winchester, MA (US);

Victoria Jane Philbin, Boston, MA (US);

Sudhir Agrawal, Shrewsbury, MA (US);

Inventors:

Ekambar Kandimalla, Southborough, MA (US);

Tao Lan, Winchester, MA (US);

Victoria Jane Philbin, Boston, MA (US);

Sudhir Agrawal, Shrewsbury, MA (US);

Assignee:

Idera Pharmaceuticals, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

TLR3 agonist compounds, compositions and methods are provided for stimulating the activity of TLR3. The compositions comprise oligonucleotide-based compounds that bind to and activate TLR3. The compositions may also comprise oligonucleotide-based compounds that bind to and activate TLR3 in combination with other therapeutic and/or prophylactic compounds and/or compositions. Methods of using these compounds and compositions for stimulation of TLR3 activity and for prevention or treatment of diseases wherein modulation of TLR3 activity would be beneficial are provided.


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