The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2013
Filed:
Jan. 19, 2010
Applicants:
Rina Rosin-arbesfeld, Herzliya, IL;
Ella Sklan, Raanana, IL;
Alona Zilberberg, Tel Aviv, IL;
Naama David, Givatayim, IL;
Inventors:
Rina Rosin-Arbesfeld, Herzliya, IL;
Ella Sklan, Raanana, IL;
Alona Zilberberg, Tel Aviv, IL;
Naama David, Givatayim, IL;
Assignee:
Ramot at Tel Aviv University, Ltd., Tel Aviv, IL;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides a nucleic acid construct comprising a promoter sequence derived from microRNA-21 (miR-21) linked to a nucleic acid sequence encoding an anti-cancer agent, an example of which is a toxin. The constructs of the invention are particularly useful for treating tumors expressing miR-21.