The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 16, 2013

Filed:

Nov. 09, 2011
Applicants:

Arthur R. Gomtsyan, Vernon Hills, IL (US);

Erol K. Bayburt, Gurnee, IL (US);

John R. Koenig, Chicago, IL (US);

Chih-hung Lee, Vernon Hills, IL (US);

Robert G. Schmidt, Waukegan, IL (US);

Kirill A. Lukin, Vernon Hills, IL (US);

Gilles Chambournier, Ann Arbor, MI (US);

Margaret Chi-ping Hsu, Lake Forest, IL (US);

Robert M. Leanna, Grayslake, IL (US);

Russell D. Cink, Grayslake, IL (US);

Inventors:

Arthur R. Gomtsyan, Vernon Hills, IL (US);

Erol K. Bayburt, Gurnee, IL (US);

John R. Koenig, Chicago, IL (US);

Chih-Hung Lee, Vernon Hills, IL (US);

Robert G. Schmidt, Waukegan, IL (US);

Kirill A. Lukin, Vernon Hills, IL (US);

Gilles Chambournier, Ann Arbor, MI (US);

Margaret Chi-Ping Hsu, Lake Forest, IL (US);

Robert M. Leanna, Grayslake, IL (US);

Russell D. Cink, Grayslake, IL (US);

Assignee:

AbbVie Inc., North Chicago, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/56 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses novel compounds of general formula (I) or a pharmaceutically acceptable salt or prodrug thereof (in which X-X, R-R, Z-Zand Arare defined herein), a method for inhibiting the VR1 receptor in mammals using these compounds, a method for controlling pain in mammals, and pharmaceutical compositions including those compounds and a process for making those compounds.


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