The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2013
Filed:
Dec. 23, 2009
Omar Rkyek, Kassel, DE;
Marc Nazare, Frankfurt am Main, DE;
Andreas Lindenschmidt, Frankfurt am Main, DE;
Matthias Urmann, Frankfurt am Main, DE;
Nis Halland, Frankfurt am Main, DE;
Jorge Alonso, Mannheim, DE;
Omar Rkyek, Kassel, DE;
Marc Nazare, Frankfurt am Main, DE;
Andreas Lindenschmidt, Frankfurt am Main, DE;
Matthias Urmann, Frankfurt am Main, DE;
Nis Halland, Frankfurt am Main, DE;
Jorge Alonso, Mannheim, DE;
Sanofi, Paris, FR;
Abstract
The present invention relates to a process for the regioselective synthesis of compounds of the formula (I), wherein R1; R2; R3; R4; R5; J and W have the meanings indicated in the claims. The present invention provides an efficient and general palladium-catalyzed coupling process for aryl tosylates with terminal alkynes to a wide variety of substituted, multifunctional aryl-1-alkynes of the formula I.