The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2013
Filed:
Oct. 04, 2011
Tony Klink, Madison, WI (US);
Jane Beebe, Elkhorn, WI (US);
David Lasky, Madison, WI (US);
Karen Kleman-leyer, Madison, WI (US);
Richard Somberg, Madison, WI (US);
Tony Klink, Madison, WI (US);
Jane Beebe, Elkhorn, WI (US);
David Lasky, Madison, WI (US);
Karen Kleman-Leyer, Madison, WI (US);
Richard Somberg, Madison, WI (US);
Life Technologies Corporation, Carlsbad, CA (US);
Abstract
Compositions, methods, and kits for detecting and monitoring kinase, phosphatase and protein post-translational modification activity are described. The compositions typically include a peptide, a detectable moiety, and a protease cleavage site. Modification of a peptide by a kinase, phosphatase or other protein post-translational modification alters the proteolytic sensitivity of the peptide, resulting in a change of a detectable property of the composition. Panel assays for determining substrates or modulators of kinase, phosphatase or other protein post-translational modification activity are also described.