The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2013
Filed:
Oct. 19, 2007
Richard Beliveau, Montreal, CA;
Michel Demeule, Beaconsfield, CA;
Stephane Barakat, Montreal, CA;
Jonathan Michaud-levesque, Montreal, CA;
Richard Beliveau, Montreal, CA;
Michel Demeule, Beaconsfield, CA;
Stephane Barakat, Montreal, CA;
Jonathan Michaud-Levesque, Montreal, CA;
Angiochem Inc., Montreal, CA;
Abstract
The present invention is directed to polypeptides (e.g., fragments) derived from P-glycoprotein and caveolin-1 which are capable of inhibiting the interaction between these two proteins. Inhibition of this interaction leads to increase of efflux of compounds that are transported by P-gp. The invention further includes methods of treating patients having diseases that benefit from increased P-gp-mediated efflux. Such diseases include neoplasms such as cancer and neurological diseases such as neurodegenerative diseases.