The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2013
Filed:
Aug. 05, 2009
Eric Valeur, Bretigny sur Orge, FR;
Franck Lepifre, Longjumeau, FR;
Didier Roche, Saclay, FR;
Denis Carniato, Antony, FR;
Serge Christmann-franck, Antony, FR;
Fabien Schmidlin, Mondeville, FR;
Eric Valeur, Bretigny sur Orge, FR;
Franck Lepifre, Longjumeau, FR;
Didier Roche, Saclay, FR;
Denis Carniato, Antony, FR;
Serge Christmann-Franck, Antony, FR;
Fabien Schmidlin, Mondeville, FR;
Merck Patent GmbH, Darmstadt, DE;
Abstract
The present invention relates to fused pyrrolidino-cyclopropane derivatives according to formulae (I) to (IV) as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11-β-HSD-1) and the use of such compounds for the treatment and/or prevention of metabolic syndrome, diabetes, insulin resistance, obesity, lipid disorders, glaucoma, osteoporosis, cognitive disorders, anxiety, depression, immune disorders, hypertension and other diseases and conditions.