The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2013
Filed:
Sep. 19, 2012
Applicants:
Dongsu Park, Houston, TX (US);
David Spencer, Houston, TX (US);
Natalia Lapteva, Houston, TX (US);
Inventors:
Assignee:
Bellicum Pharmaceuticals, Inc., Houston, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/07 (2010.01); C12N 5/0784 (2010.01); C12N 5/10 (2006.01);
U.S. Cl.
CPC ...
Abstract
Modified antigen presenting cells provided herein have improved lifespan and immunogenicity compared to unmodified antigen presenting cells, and are useful for immunotherapy. The modified antigen presenting cells express an altered protein kinase, referred to herein as 'Akt.' The altered Akt associates with the cell membrane with greater frequency than unaltered Akt, and is referred to herein as 'membrane-targeted Akt.'