The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2013
Filed:
Mar. 21, 2008
Phillip R. Fleshner, Los Angeles, CA (US);
Eric A. Vasiliauskas, Manhattan Beach, CA (US);
Gil Melmed, Los Angeles, CA (US);
Stephan R. Targan, Santa Monica, CA (US);
Phillip R. Fleshner, Los Angeles, CA (US);
Eric A. Vasiliauskas, Manhattan Beach, CA (US);
Gil Melmed, Los Angeles, CA (US);
Stephan R. Targan, Santa Monica, CA (US);
Cedars-Sinai Medical Center, Los Angeles, CA (US);
Abstract
A common long term problem after Ileal Pouch-Anal Anastomosis (IPAA) is the inflammation of the pouch, called pouchitis. Additionally, about 5-10% of patients undergoing IPAA with a diagnosis of ulcerative colitis at the time of surgery are subsequently diagnosed with Crohn's disease. In one embodiment, the present invention provides methods of diagnosing and predicting susceptibility to pouchitis after IPAA by detecting the presence or absence of pANCA and/or Cbir1 Flagellin expression.