The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2013
Filed:
Nov. 17, 2011
Applicants:
Jack A. Tuszynski, Edmonton, CA;
Chih-yuan Tseng, Edmonton, CA;
Inventors:
Jack A. Tuszynski, Edmonton, CA;
Chih-Yuan Tseng, Edmonton, CA;
Assignee:
Technology Innovations, LLC, West Henrietta, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06G 7/48 (2006.01); G06F 17/11 (2006.01); G06F 17/50 (2006.01);
U.S. Cl.
CPC ...
Abstract
Disclosed in this specification is a method for identifying at least one aptamer that can bind to a bio-molecular target. The aptamer is designed in silico based on the structure of the target molecule. The process includes the steps of determining a first seed residue and growing an oligomer, one residue at a time, while maximizing the entropy of target-oligomer complex or minimizing the binding energy after the addition of each oligomer.