The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2013
Filed:
Nov. 10, 2011
Graham Beaton, Poway, CA (US);
MI Chen, San Diego, CA (US);
Timothy Richard Coon, Carlsbad, CA (US);
Todd Ewing, San Diego, CA (US);
Wanlong Jiang, San Diego, CA (US);
Richard Lowe, Oakland, CA (US);
Willy Moree, San Diego, CA (US);
Nicole Smith, San Diego, CA (US);
Warren Wade, San Diego, CA (US);
Liren Zhao, San Diego, CA (US);
Yun-fei Zhu, San Diego, CA (US);
Martin Rowbottom, San Diego, CA (US);
Neil Ashweek, San Diego, CA (US);
Graham Beaton, Poway, CA (US);
Mi Chen, San Diego, CA (US);
Timothy Richard Coon, Carlsbad, CA (US);
Todd Ewing, San Diego, CA (US);
Wanlong Jiang, San Diego, CA (US);
Richard Lowe, Oakland, CA (US);
Willy Moree, San Diego, CA (US);
Nicole Smith, San Diego, CA (US);
Warren Wade, San Diego, CA (US);
Liren Zhao, San Diego, CA (US);
Yun-fei Zhu, San Diego, CA (US);
Martin Rowbottom, San Diego, CA (US);
Neil Ashweek, San Diego, CA (US);
Neurocrine Biosciences, Inc., San Diego, CA (US);
Abstract
GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein R, R, R, R, R, R, and A are as defined herein, including stereoisomers, esters, solvates and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.