The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2013
Filed:
May. 25, 2010
Peiyuan Wang, Glen Rock, NJ (US);
Wojciech Stec, Ksawerow, PL;
Byoung Kwon Chun, Robbinsville, NJ (US);
Junxing Shi, Duluth, GA (US);
Jinfa Du, New Hope, PA (US);
Peiyuan Wang, Glen Rock, NJ (US);
Wojciech Stec, Ksawerow, PL;
Byoung Kwon Chun, Robbinsville, NJ (US);
Junxing Shi, Duluth, GA (US);
Jinfa Du, New Hope, PA (US);
Gilead Pharmasset LLC, Foster City, CA (US);
Abstract
The present invention provides (i) a process for preparing a 2-deoxy-2-fluoro-2-methyl-D-ribonolactone derivative, (ii) conversion of the lactone to nucleosides with potent anti-HCV activity, and their analogues, and (iii) a method to prepare the anti-HCV nucleosides containing the 2-deoxy-2-fluoro-2-C-methyl-β-D-ribofuranosyl nucleosides from a preformed, preferably naturally-occurring, nucleoside.