The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 09, 2013

Filed:

May. 06, 2008
Applicants:

Patrício Manuel Vieira Araújo Soares Da Silva, Oporto, PT;

David Alexander Learmonth, Alfena, PT;

Alexander Beliaev, Mindelo, PT;

Assignee:

Bial-Portela & CA, S.A., S. Mamede Do Coronado, PT;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4178 (2006.01); C07D 207/48 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of formula I and a method for their preparation are described: where R, Rand Rare the same or different and signify hydrogens, halogens, alkyl, nitro, amino, alkylcarbonylamino, alkylamino or dialkylamino group; Rsignifies -alkyl-aryl or -alkyl-heteroaryl; X signifies CH, oxygen atom or sulphur atom; n is 2 or 3; including the individual (R)- and (S)-enantiomers or mixtures of enantiomers thereof; and including pharmaceutically acceptable salts and esters thereof. The compounds have potentially valuable pharmaceutical properties for the treatment of cardiovascular disorders such as hypertension and chronic heart failure.


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