The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2013
Filed:
Jan. 26, 2010
Thomas Schrader, Mettmann, DE;
Katrin Hochdörffer, Freiburg, DE;
Julia März-berberich, Essen, DE;
Luitgard Nagel-steger, Langenfeld, DE;
Gal Bitan, Los Angeles, CA (US);
Sharmistha Sinha, Ames, IA (US);
Thomas Schrader, Mettmann, DE;
Katrin Hochdörffer, Freiburg, DE;
Julia März-Berberich, Essen, DE;
Luitgard Nagel-Steger, Langenfeld, DE;
Gal Bitan, Los Angeles, CA (US);
Sharmistha Sinha, Ames, IA (US);
Other;
Abstract
The present invention relates to the field of protein misfolding diseases and thus to diseases which are associated with or induced by abnormal or pathogenic three-dimensional folding of proteins and/or peptides or which are linked to pathogenic conformational changes of proteins and/or peptides, such as Alzheimer's disease. Particularly, the present invention provides novel trimeric pyrazole compounds, which exhibit a therapeutic effectiveness in regard to the aforementioned protein misfolding diseases, and refers to their use for the treatment of such protein misfolding diseases, especially neurodegenerative diseases as well as to medicaments or pharmaceutical compositions comprising these compounds.