The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 09, 2013

Filed:

Jul. 21, 2008
Applicants:

Karl M. Schumacher, Singapore, SG;

Jackie Y. Ying, Singapore, SG;

Annegret Schumacher, Singapore, SG;

Karthikeyan Narayanan, Singapore, SG;

Gunter Maubach, Singapore, SG;

Inventors:

Karl M. Schumacher, Singapore, SG;

Jackie Y. Ying, Singapore, SG;

Annegret Schumacher, Singapore, SG;

Karthikeyan Narayanan, Singapore, SG;

Gunter Maubach, Singapore, SG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to methods of differentiating a human embryonic stem (ES) cell into a cell, specifically a renal epithelial cell, expressing AQP-I. The methods disclosed comprise culturing human ES cells in a renal specific medium in the presence of an extracellular matrix molecule. The cells produced according to said method can be used to treat renal related disorders such as renal failure, nephrosis, Bright's disease and glomerulitis.


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