The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2013
Filed:
Sep. 26, 2007
Inger Andersson, Storvreta, SE;
Andreas Axen, Jarlasa, SE;
Peder Bergvall, Uppsala, SE;
John Clachan, Uppsala, SE;
Camilla Estmer-nilsson, Uppsala, SE;
Lena M. Sandberg, Uppsala, SE;
Inger Andersson, Storvreta, SE;
Andreas Axen, Jarlasa, SE;
Peder Bergvall, Uppsala, SE;
John Clachan, Uppsala, SE;
Camilla Estmer-Nilsson, Uppsala, SE;
Lena M. Sandberg, Uppsala, SE;
GE Healthcare Bio-Sciences AB, Uppsala, SE;
Abstract
The present invention relates to a method of preparing a separation matrix comprising at least one insoluble carrier to which sulphate ligands have been attached via extenders, which method comprises coupling, in a first step, of the sulphate ligands to the extenders and, in a subsequent step, attaching the extenders to an insoluble carrier. The invention also relates to a separation matrix comprised of at least one insoluble carrier to which sulphate ligands have been attached via extenders. Advantageously, no sulphate ligands are directly attached to the insoluble carrier. The extenders may be natural polymers, such as dextran, and the insoluble carrier may be made from natural polymers, such as agarose, or synthetic polymers. The invention also relates to a method of purifying virus, such as influenza virus, using a separation matrix according to the invention.