The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 09, 2013

Filed:

Nov. 24, 2005
Applicants:

Fanny Longin, Frederiksberg, DK;

Khadija Schwach-abdellaoui, Frederiksberg, DK;

Inventors:

Fanny Longin, Frederiksberg, DK;

Khadija Schwach-Abdellaoui, Frederiksberg, DK;

Assignee:

Novozymes Biopolymer A/S, Bagsvaerd, DK;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to methods of producing a homogenous hydrogel comprising hyaluronic acid, or salt thereof, crosslinked with divinylsulfone (DVS), said method comprising the steps of (a) providing an alkaline solution of hyaluronic acid, or salt thereof; (b) adding DVS to the solution of step (a), whereby the hyaluronic acid, or salt thereof, is crosslinked with the DVS to form a gel; (c) treating the gel of step (b) with a buffer, wherein the gel swells and forms a hydrogel comprising hyaluronic acid, or salt thereof, crosslinked with DVS.


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