The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 09, 2013

Filed:

Feb. 03, 2012
Applicants:

Eisuke Mekada, Osaka, JP;

Ryo Iwamoto, Osaka, JP;

Shingo Miyamoto, Fukuoka, JP;

Kenya Shitara, Tokyo, JP;

Akiko Furuya, Tokyo, JP;

Kazuyasu Nakamura, Tokyo, JP;

Kumiko Takahashi, Cambridge, MA (US);

Hiroshi Ando, Tokyo, JP;

Kazuhiro Masuda, Tokyo, JP;

Yuka Sasaki, Tokyo, JP;

Inventors:

Eisuke Mekada, Osaka, JP;

Ryo Iwamoto, Osaka, JP;

Shingo Miyamoto, Fukuoka, JP;

Kenya Shitara, Tokyo, JP;

Akiko Furuya, Tokyo, JP;

Kazuyasu Nakamura, Tokyo, JP;

Kumiko Takahashi, Cambridge, MA (US);

Hiroshi Ando, Tokyo, JP;

Kazuhiro Masuda, Tokyo, JP;

Yuka Sasaki, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 39/00 (2006.01); C12P 21/08 (2006.01); C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39558 (2013.01);
Abstract

Medicaments for treating diseases related to HB-EGF escalation are in demand. The present invention provides a monoclonal antibody or an antibody fragment thereof which binds to a cell membrane-bound HB-EGF, a membrane type HB-EGF and a secretory HB-EGF.


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