The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2013
Filed:
Jun. 22, 2011
Applicants:
Che-kun James Shen, Taipei, TW;
Lien-szu Wu, Tainan, TW;
Inventors:
Che-Kun James Shen, Taipei, TW;
Lien-Szu Wu, Tainan, TW;
Assignee:
Academia Sinica, Taipei, TW;
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/027 (2006.01); G01N 33/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
A non-human animal model for amyotrophic lateral sclerosis (ALS) is disclosed. The animal model comprises a rodent whose spinal cord motor neurons have a loss of TAR-DNA binding protein-43 (TDP-43) function and phenotypes exhibit ALS-like symptoms. A method for identifying a candidate agent for treating, preventing and/or inhibiting ALS associated with a loss-of-function of TDP-43 is also disclosed.