The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2013

Filed:

Jun. 30, 2011
Applicants:

Hyun Ju, Yongin-si, KR;

Sang-sun Joung, Hwaseong-si, KR;

Hyun-jik Yi, Yongin-si, KR;

Ja-heouk Khoo, Gunpo-si, KR;

Jong-chul Lim, Yongin-si, KR;

Jae-gyu Kim, Seoul, KR;

Inventors:

Hyun Ju, Yongin-si, KR;

Sang-Sun Joung, Hwaseong-si, KR;

Hyun-Jik Yi, Yongin-si, KR;

Ja-Heouk Khoo, Gunpo-si, KR;

Jong-Chul Lim, Yongin-si, KR;

Jae-Gyu Kim, Seoul, KR;

Assignee:

Yuhan Corporation, Seoul, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/42 (2006.01); C07D 215/12 (2006.01); C07D 405/06 (2006.01); C07D 209/10 (2006.01); C07D 257/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides an improved process for preparing HMG-CoA reductase inhibitors such as rosuvastatin calcium, fluvastatin sodium, and pitavastatin calcium under a mild condition, using a novel amide-bond-containing compound having R—N—O—Rmoiety as a key intermediate. And also, the present invention provides the novel compound, an intermediate useful for the preparation thereof, and a process for the preparation thereof.


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