The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2013
Filed:
Dec. 04, 2008
Mark H. Norman, Thousand Oaks, CA (US);
Yunxin Y. BO, Thousand Oaks, CA (US);
Vijay K. Gore, Thousand Oaks, CA (US);
Daniel Horne, Thousand Oaks, CA (US);
Matthew Kaller, Ventura, CA (US);
VU Van MA, Simi Valley, CA (US);
Holger Monenschein, Camarillo, CA (US);
Thomas Nguyen, Thousand Oaks, CA (US);
Nobuko Nishimura, West Hills, CA (US);
Nuria Tamayo, Newbury Park, CA (US);
Mark H. Norman, Thousand Oaks, CA (US);
Yunxin Y. Bo, Thousand Oaks, CA (US);
Vijay K. Gore, Thousand Oaks, CA (US);
Daniel Horne, Thousand Oaks, CA (US);
Matthew Kaller, Ventura, CA (US);
Vu Van Ma, Simi Valley, CA (US);
Holger Monenschein, Camarillo, CA (US);
Thomas Nguyen, Thousand Oaks, CA (US);
Nobuko Nishimura, West Hills, CA (US);
Nuria Tamayo, Newbury Park, CA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
Tetrahydroisoquinoline compounds of formula (I), and compositions containing them, for the treatment of acute, inflammatory and neurophatic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neurophatic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.