The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2013
Filed:
May. 27, 2011
Wilfried Braje, Rintein, DE;
Andreas Haupt, Schwetzingen, DE;
Wilfried Lubisch, Heidelberg, DE;
Roland Grandel, Dossenheim, DE;
Karla Drescher, Dossenheim, DE;
Herve Geneste, Neuhofen, DE;
Liliane Unger, Ludwigshafen, DE;
Daryl R. Sauer, Trevor, WI (US);
Sean Colm Turner, Mannheim, DE;
Wilfried Braje, Rintein, DE;
Andreas Haupt, Schwetzingen, DE;
Wilfried Lubisch, Heidelberg, DE;
Roland Grandel, Dossenheim, DE;
Karla Drescher, Dossenheim, DE;
Herve Geneste, Neuhofen, DE;
Liliane Unger, Ludwigshafen, DE;
Daryl R. Sauer, Trevor, WI (US);
Sean Colm Turner, Mannheim, DE;
Abbott GmbH & Co. KG, Wiesbaden, DE;
Abstract
The invention related to N-[(piperazinyl)hetaryl]arylsulfonamide compounds of the general formula (I) in which Q is a bivalent, 6-membered heteroaromatic radical which possesses 1 or 2 N atoms as ring members and which optionally carries one or two substituents Rwhich is/are selected, independently of each other, from halogen, CN, NO, COR, COR, C-C-alkyl and C-C-haloalkyl; Ar is phenyl or a 6-membered heteroaromatic radical which possesses 1 or 2 N atoms as ring members and which optionally carries one or two substituents R, which is/are selected from halogen, NO, CN, COR, COR, C-C-alkyl, C-C-alkenyl, C-C-alkynyl, C-C-cycloalkyl, C-C-cycloalkyl-C-C-alkyl and C-C-haloalkyl, with it also being possible for two radicals Rwhich are bonded to adjacent C atoms of Ar to be together C-C-alkylene; Ris hydrogen, C-C-alkyl, C-C-haloalkyl, C-C-cycloalkyl, C-C-cycloalkyl-C-C-alkyl, C-C-hydroxyalkyl, C-C-alkoxy-C-C-alkyl, C-C-alkenyl or C-C-alkynyl; with the radicals n, R, R, R, Rand Rhaving the meanings given in the patent claims, to the N-oxides and to the physiologically tolerated acid addition salts of these compounds and to pharmaceutical compositions which comprise at least one N-[(piperazinyl)hetaryl]arylsulfonamide compound as claimed in one of claimstoand/or at least one physiologically tolerated acid addition salt of I and/or an N-oxide of I, where appropriate together with physiologically acceptable carriers and/or auxiliary substances for treating diseases which respond to influencing by dopamine Dreceptor antagonists or agonists, in particular for treating diseases of the central nervous system and disturbances of kidney function.