The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2013

Filed:

Sep. 12, 2008
Applicants:

Oana Cociorva, San Diego, CA (US);

Yasumichi Fukuda, Shimotsuga-gun, JP;

Yasushi Kohno, Shimotsuga-gun, JP;

Bei LI, San Diego, CA (US);

Kyoko Okada, Shimotsuga-gun, JP;

Ayako Nakamura, Shimotsuga-gun, JP;

Masahiro Nomura, Shimotsuga-gun, JP;

Shigeki Seto, Shimotsuga-gun, JP;

Anna Katrin Szardenings, Torrance, CA (US);

Kazuhiro Yumoto, Shimotsuga-gun, JP;

Inventors:

Oana Cociorva, San Diego, CA (US);

Yasumichi Fukuda, Shimotsuga-gun, JP;

Yasushi Kohno, Shimotsuga-gun, JP;

Bei Li, San Diego, CA (US);

Kyoko Okada, Shimotsuga-gun, JP;

Ayako Nakamura, Shimotsuga-gun, JP;

Masahiro Nomura, Shimotsuga-gun, JP;

Shigeki Seto, Shimotsuga-gun, JP;

Anna Katrin Szardenings, Torrance, CA (US);

Kazuhiro Yumoto, Shimotsuga-gun, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5386 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided herein are spirocyclic aminoquinolones of formula I and compositions containing the compounds. The compounds and compositions provided herein are useful in the prevention, amelioration or treatment of GSK-3 inhibitors mediated diseases. In Formula (I): Xis O or NR; A is bond or substituted or unsubstituted C-Calkylene, wherein the substituents when present are selected from one to four Qgroups; where Qis alkyl or haloalkyl; p is 0 or 1; and q is an integer of 0 to 2.


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