The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2013
Filed:
Mar. 25, 2011
Norman N. Kim, Westford, MA (US);
William K. Mcvicar, Sudbury, MA (US);
Thomas G. Mccauley, Cambridge, MA (US);
Prakash Jagtap, N. Andover, MA (US);
Norman N. Kim, Westford, MA (US);
William K. McVicar, Sudbury, MA (US);
Thomas G. McCauley, Cambridge, MA (US);
Prakash Jagtap, N. Andover, MA (US);
Inotek Pharmaceuticals Corporation, Lexington, MA (US);
Abstract
Provided herein is a method of reducing intraocular pressure (IOP) in humans using N6-cyclopentyladenosine (CPA), CPA derivatives or prodrugs or enhanced cornea permeability formulations of CPA. In one embodiment, the invention is directed to CPA derivatives or prodrugs that are permeable to the cornea. In another embodiment, the invention is directed to uses of certain compounds in human subjects for reducing and/or controlling elevated or abnormally fluctuating IOPs in the treatment of glaucoma or ocular hypertension (OHT).