The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2013
Filed:
Jul. 30, 2010
Karl-hermann Schlingensiepen, Donaustauf, DE;
Frank Jaschinski, Obertraubling, DE;
Tanja Rothammer-hampl, Haibach, DE;
Anneliese Schneider, Feldafing, DE;
Karl-Hermann Schlingensiepen, Donaustauf, DE;
Frank Jaschinski, Obertraubling, DE;
Tanja Rothammer-Hampl, Haibach, DE;
Anneliese Schneider, Feldafing, DE;
Antisense Pharma GmbH, Regensburg, DE;
Abstract
Pharmaceutical composition comprising a chemotherapeutic agent and a TGF-beta antisense oligonucleotide, wherein the antisense oligonucleotide reduces the sensitivity and IC, respectively, of the cytotoxicity of the chemotherapeutic agent. Preferably, the antisense oligonucleotide is a TGF-beta 1, 2, and/or 3 antisense oligonucleotide and the chemotherapeutic agent is preferably gemcitabine, 5-fluorouracil, temozolomide, dacarbacine, docetaxel, cisplatin, oxaliplatin, tamoxifen, or irinotecan.