The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2013
Filed:
Oct. 14, 2011
János Tibor Kodra, København Ø, DK;
Patrick William Garibay, Holte, DK;
Thomas Hoeg-jensen, Klampenborg, DK;
Ib Jonassen, Valby, DK;
Peter Madsen, Bagsværd, DK;
Tina Møller Tagmose, Ballerup, DK;
János Tibor Kodra, København Ø, DK;
Patrick William Garibay, Holte, DK;
Thomas Hoeg-Jensen, Klampenborg, DK;
Ib Jonassen, Valby, DK;
Peter Madsen, Bagsværd, DK;
Tina Møller Tagmose, Ballerup, DK;
Novo Nordisk A/S, Bagsvaerd, DK;
Abstract
The present invention relates to insulin derivatives having a side chain attached either to the α-amino group of the N-terminal amino acid residue of the B chain or to the ε-amino group of a Lys residue present in the B chain of the parent insulin via an amide bond which side chain comprises at least one aromatic group; at least one free carboxylic acid group or a group which is negatively charged at neutral pH, a fatty acid moiety with 4 to 22 carbon atoms in the carbon chain; and possible linkers which link the individual components in the side chain together via amide bonds.