The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2013
Filed:
Sep. 20, 2010
Applicants:
James K. Kranz, Pottstown, PA (US);
Gabrielle C. Todd, Ann Arbor, MI (US);
Matthew J. Todd, Downingtown, PA (US);
Inventors:
James K. Kranz, Pottstown, PA (US);
Gabrielle C. Todd, Ann Arbor, MI (US);
Matthew J. Todd, Downingtown, PA (US);
Assignee:
Janssen Pharmaceutica NV, Beerse, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/566 (2006.01);
U.S. Cl.
CPC ...
G01N 33/566 (2013.01);
Abstract
A method for identifying a ligand or compound which binds to albumin comprises the steps of contacting a reaction mixture comprising a site-specific probe and albumin in the presence and the absence of the ligand or compound and measuring either dissociation constant K, inhibitor concentration ICor fluorescence displacement; whereby a change in K, ICand/or fluorescence in the presence of the ligand or compound is indicative of the ligand or compound binds to albumin.