The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8470863 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 25, 2013

Filed:

Feb. 11, 2008
Applicants:

Junying Zheng, New Providence, NJ (US);

Kevin D. Mccormick, Basking Ridge, NJ (US);

Jianhua Chao, San Diego, CA (US);

Christopher W. Boyce, Flemington, NJ (US);

Robert G. Aslanian, Rockaway, NJ (US);

Younong Yu, East Brunswick, NJ (US);

Inventors:

Junying Zheng, New Providence, NJ (US);

Kevin D. McCormick, Basking Ridge, NJ (US);

Jianhua Chao, San Diego, CA (US);

Christopher W. Boyce, Flemington, NJ (US);

Robert G. Aslanian, Rockaway, NJ (US);

Younong Yu, East Brunswick, NJ (US);

Assignee:

Merck Sharp & Dohme, Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4178 (2006.01); C07D 233/64 (2006.01);
U.S. Cl.
CPC ...
Abstract

In its many embodiments, the present invention provides a novel class of chroman compounds of formula I as α2C adrenergic receptor agonists, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of prepaxing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more conditions associated with the α2C adrenergic receptors using such compounds or pharmaceutical compositions.


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