The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2013
Filed:
Jan. 27, 2010
Marion W. Anders, Pittsford, NY (US);
James L. Robotham, Seattle, WA (US);
Shey-shing Sheu, Pittsford, NY (US);
Paul Spencer Brookes, Rochester, NY (US);
Jalil Shojaie, Rochester, NY (US);
Leif Olson, Riverside, RI (US);
Richard L. Parton, Webster, NY (US);
Marion W. Anders, Pittsford, NY (US);
James L. Robotham, Seattle, WA (US);
Shey-Shing Sheu, Pittsford, NY (US);
Paul Spencer Brookes, Rochester, NY (US);
Jalil Shojaie, Rochester, NY (US);
Leif Olson, Riverside, RI (US);
Richard L. Parton, Webster, NY (US);
University of Rochester, Rochester, NY (US);
Abstract
The present invention is a mitochondria-targeted antioxidant prodrug useful for the prevention or treatment of diseases or conditions associated with mitochondrial dysfunction resulting from changes in the mitochondrial redox environment. Antioxidant prodrugs of the invention are produced by modifying an antioxidant to a fatty acid so that the resulting prodrug is targeted to and activated by an enzyme of mitochondrial fatty acid beta-oxidation.