The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2013
Filed:
Aug. 19, 2009
Cecil D. Kwong, Birmingham, AL (US);
F. George Njoroge, Warren, NJ (US);
Subramaniam Ananthan, Birmingham, AL (US);
Feng Geng, Piscataway, NJ (US);
Hollis S. Kezar, Iii, Hoover, AL (US);
Joseph A. Maddry, Birmingham, AL (US);
John J. Piwinski, Lebanon, NJ (US);
Robert C. Reynolds, Birmingham, AL (US);
John A. Secrist, Iii, Birmingham, AL (US);
Neng-yang Shih, Lexington, MA (US);
Cecil D. Kwong, Birmingham, AL (US);
F. George Njoroge, Warren, NJ (US);
Subramaniam Ananthan, Birmingham, AL (US);
Feng Geng, Piscataway, NJ (US);
Hollis S. Kezar, III, Hoover, AL (US);
Joseph A. Maddry, Birmingham, AL (US);
John J. Piwinski, Lebanon, NJ (US);
Robert C. Reynolds, Birmingham, AL (US);
John A. Secrist, III, Birmingham, AL (US);
Neng-Yang Shih, Lexington, MA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Southern Research Institute, Birmingham, AL (US);
Abstract
The present invention provides compounds of Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R, X, Y, Z, R, R, R, R, R, R, R, R, R, R, and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.