The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2013
Filed:
Sep. 23, 2009
Daniele Fancelli, Milan, IT;
Mario Varasi, Milan, IT;
Simon Plyte, Cadorago, IT;
Marco Ballarini, Milan, IT;
Anna Cappa, Visso, IT;
Giacomo Carenzi, Busto Arsizio, IT;
Saverio Minucci, Noverasco di Opera, IT;
Gilles Pain, Castelforte, IT;
Manuela Villa, Lurago d'Erba, IT;
Daniele Fancelli, Milan, IT;
Mario Varasi, Milan, IT;
Simon Plyte, Cadorago, IT;
Marco Ballarini, Milan, IT;
Anna Cappa, Visso, IT;
Giacomo Carenzi, Busto Arsizio, IT;
Saverio Minucci, Noverasco di Opera, IT;
Gilles Pain, Castelforte, IT;
Manuela Villa, Lurago d'Erba, IT;
Cogenia SRL, Milan, IT;
Abstract
Acrylamido derivatives useful as therapeutic agents, particularly for the prevention and/or treatment of diseases and conditions associated with the activity of the mitochondrial permeability transition pore (MPTP), such as the diseases characterized by ischemia/reperfusion, oxidative or degenerative tissue damage, are herein described. These compounds belong to the structural formula (I) wherein R, R', R″, W and a are as defined in the specification. The invention also relates to the preparation of these compounds, as well as to pharmaceutical compositions comprising them.