The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2013

Filed:

Oct. 26, 2009
Applicants:

Lin Chu, Scotch Plains, NJ (US);

Anthony Ogawa, Mountainside, NJ (US);

Hyun O. OK, Colonia, NJ (US);

Feroze Ujjainwalla, Scotch Plains, NJ (US);

Inventors:

Lin Chu, Scotch Plains, NJ (US);

Anthony Ogawa, Mountainside, NJ (US);

Hyun O. Ok, Colonia, NJ (US);

Feroze Ujjainwalla, Scotch Plains, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); A61K 31/44 (2006.01); A61K 31/41 (2006.01); C07D 403/14 (2006.01); C07D 413/14 (2006.01); C07D 249/08 (2006.01); C07D 271/10 (2006.01); C07D 417/14 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides compounds of Formula I which are PAFR antagonists: I and the pharmaceutically acceptable salts thereof. The compounds are useful for treating PAF-mediated disorders, and can be used in methods for treating atherosclerosis and preventing or reducing risk for atherosclerotic disease events. The compounds are also useful for treating or ameliorating pain, e.g. inflammatory pain and/or nociceptive pain, and for treating or ameliorating autoimmune and/or inflammatory diseases, among other conditions.


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