The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2013

Filed:

Sep. 17, 2008
Applicants:

Douglas B. Jacoby, Wellesley, MA (US);

Abdellah Sentissi, Dover, MA (US);

E. Michael Egan, Brookline, MA (US);

Kamala Kesavan, West Roxbury, MA (US);

Inventors:

Douglas B. Jacoby, Wellesley, MA (US);

Abdellah Sentissi, Dover, MA (US);

E. Michael Egan, Brookline, MA (US);

Kamala Kesavan, West Roxbury, MA (US);

Assignee:

Morphotek, Inc., Exton, PA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/566 (2006.01); G01N 33/53 (2006.01); C12N 5/00 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to novel methods of inhibiting angiogenesis using chlorotoxin agents. In some embodiments, the inventive methods include intravenous, intraocular, intravitreal, subjunctival injection, and/or topical administration of a chlorotoxin agent that may or may not be labeled. In some embodiments, the inventive methods allow treatment and/or amelioration of ocular diseases characterized by neovascularization, such as wet macular degeneration. In some embodiments, neovascularization is inhibited and/or newly formed vessels are caused to regress.


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