The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 25, 2013

Filed:

Oct. 12, 2010
Applicants:

Matthew S. Croughan, Claremont, CA (US);

Nathaniel W. Freund, Camarillo, CA (US);

Inventors:

Matthew S. Croughan, Claremont, CA (US);

Nathaniel W. Freund, Camarillo, CA (US);

Assignee:

Keck Graduate Institute, Claremont, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 21/06 (2006.01); C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12N 15/63 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present disclosure provides a method for culturing cells in exogenous lactic acid. Certain aspects of the present disclosure include the production of recombinant proteins, such as antibodies and fragments thereof. Certain aspects of the present disclosure also relate to methods of controlling lactic acid production, pH stability and osmolality in cell culture.


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