The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2013
Filed:
May. 06, 2010
Mark Throsby, Utrecht, NL;
Robert Heinz Edward Friesen, Leiden, NL;
Theodorus Hendrikus Jacobus Kwaks, Amsterdam, NL;
Mandy Antonia Catharina Jongeneelen, Leiden, NL;
Mark Throsby, Utrecht, NL;
Robert Heinz Edward Friesen, Leiden, NL;
Theodorus Hendrikus Jacobus Kwaks, Amsterdam, NL;
Mandy Antonia Catharina Jongeneelen, Leiden, NL;
Crucell Holland B.V., Leiden, NL;
Abstract
Binding molecules, such as human monoclonal antibodies, that bind to influenza virus comprising HA of the H3 subtype, such as H3N2, and have a broad neutralizing activity against such influenza virus. Provided are nucleic acid molecules encoding the antibodies, their sequences and compositions comprising the antibodies and methods of identifying or producing the antibodies. The antibodies can be used in the diagnosis, prophylaxis and/or treatment of an influenza virus H3N2 infection. The antibodies may provide cross-subtype protection, such that infections with H3, H7, and/or H10-based influenza subtypes can be prevented and/or treated.