The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2013
Filed:
May. 03, 2010
Cristina Mateo DE Acosta Del Rio, C. Habana, CU;
Ana Maria Vazquez Lopez, C. Habana, CU;
Alejandro Lopez Requena, C. Habana, CU;
Yuniel Fernandez Marrero, C. Habana, CU;
Yosdel Soto Lopez, C. Habana, CU;
Victor Brito Navarro, C. Habana, CU;
Cristina Mateo De Acosta Del Rio, C. Habana, CU;
Ana Maria Vazquez Lopez, C. Habana, CU;
Alejandro Lopez Requena, C. Habana, CU;
Yuniel Fernandez Marrero, C. Habana, CU;
Yosdel Soto Lopez, C. Habana, CU;
Victor Brito Navarro, C. Habana, CU;
Centro de Inmunologia Molecular, Habana, CU;
Abstract
The present invention relates to the biotechnology and particularly with new products for use in human health. The present invention provides new specific monoclonal antibodies, which bind with high affinity sulfatides and sulfated proteoglycans. The anti sulfatides and anti sulfated proteoglycans antibodies disclosed in the present invention and described in the description, provide important diagnostic and therapeutic tools to act on pathological processes associated with the appearance of atherosclerotic plaques. Accordingly, the invention provides pharmaceutical compositions comprising MAbs of the invention or fragments thereof for the therapeutic and diagnostic use associated with cardiovascular diseases. Particularly, the present invention relates to the fragments derived from the MAbs that recognize sulfatides and sulfated proteoglycans, which can be used in the therapy or diagnosis of this pathology.