The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 25, 2013
Filed:
Jul. 03, 2007
Polypeptides with enhanced anti-inflammatory and decreased cytotoxic properties and relating methods
Applicants:
Jeffrey V. Ravetch, New York, NY (US);
Falk Nimmerjahn, Thumau, DE;
Yoshikatsu Kaneko, Niigata, JP;
Inventors:
Assignee:
The Rockefeller University, New York, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 47/00 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides a polypeptide containing at least one IgG Fc region, wherein said at least one IgG Fc region is glycosylated with at least one galactose moiety connected to a respective terminal sialic acid moiety by a α 2, 6 linkage, and wherein said polypeptide having a higher anti-inflammatory activity as compared to an unpurified antibody.