The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8466267 B1

PDF
Full Text
Expired
Date of Patent:
Jun. 18, 2013

Filed:

Jul. 05, 2007
Applicant:

Trevor Collingwood, Novato, CA (US);

Inventor:

Trevor Collingwood, Novato, CA (US);

Assignee:

Sangamo Biosciences, Inc., Richmond, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/00 (2006.01); C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

A variety of zinc finger proteins (ZFPs) and methods utilizing such proteins are provided for use in treating neuropathic pain. ZFPs that bind to a target site in genes that are aberrantly expressed in subjects having neuropathic pain are described. In addition, ZFPs that bind to a target site in genes expressed at normal levels in subjects experiencing neuropathic pain, modulation of whose expression results in decreased pain perception, are also provided. For example, genes that are over-expressed in the dorsal root ganglia (DRG) of pain patients (e.g., VR1, TRKA and/or Nav1.8) can be repressed, whereas genes that are under-expressed in the same populations can be activated.


Find Patent Forward Citations

Collingwood, Trevor. (2013). Nucleic acid encoding a zinc finger that recognizes the sodium channel nav 1.8 (pn3) gene (U.S. Patent No. 8466267). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8466267

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