The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 2013

Filed:

Jul. 03, 2012
Applicants:

Brent A. Appleton, San Francisco, CA (US);

Christian Wiesmann, Bottmingen, CH;

Yan Wu, Foster City, CA (US);

Inventors:

Brent A. Appleton, San Francisco, CA (US);

Christian Wiesmann, Bottmingen, CH;

Yan Wu, Foster City, CA (US);

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 19/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides crystal structures of neuropilin 1 (Nrp1) and neuropilin 2 (Nrp2) fragments alone and in complex with anti-neuropilin antibodies, and method for their use. The invention further provides anti-Nrp antibodies and methods for their therapeutic applications.


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