The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2013
Filed:
Dec. 05, 2007
Gregor James Macdonald, Zoersel, BE;
José Ignacio Andrés-gil, Madrid, ES;
Frans Alfons Maria Van Den Keybus, Essen, BE;
José Manuel Bartolomé-nebreda, Toleda, ES;
Michiel Luc Maria Van Gool, Madrid, ES;
Gregor James MacDonald, Zoersel, BE;
José Ignacio Andrés-Gil, Madrid, ES;
Frans Alfons Maria Van Den Keybus, Essen, BE;
José Manuel Bartolomé-Nebreda, Toleda, ES;
Michiel Luc Maria Van Gool, Madrid, ES;
Janssen Pharmaceutica N.V., Beerse, BE;
Abstract
The present invention relates to 6-(piperidin-4-ylamino)pyridazin-3-carbonitriles of the general formula (I); or a pharmaceutically acceptable salt thereof, or a stereoisomeric form, that are fast dissociating dopamine 2 receptor antagonists, as well as processes for preparing these compounds, pharmaceutical compositions comprising these compounds as an active ingredient. The compounds find utility as medicines for treating or preventing central nervous system disorders, for example schizophrenia, by exerting an antipsychotic effect without motor side effects.