The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 18, 2013

Filed:

Feb. 23, 2010
Applicants:

Hiroyuki Kakinuma, Toshima-ku, JP;

Yohei Kobashi, Toshima-ku, JP;

Tomomichi Chonan, Toshima-ku, JP;

Takahiro Oi, Toshima-ku, JP;

Fumiyasu Shiozawa, Toshima-ku, JP;

Yuki Iwata, Toshima-ku, JP;

Kenichi Kawabe, Toshima-ku, JP;

Inventors:

Hiroyuki Kakinuma, Toshima-ku, JP;

Yohei Kobashi, Toshima-ku, JP;

Tomomichi Chonan, Toshima-ku, JP;

Takahiro Oi, Toshima-ku, JP;

Fumiyasu Shiozawa, Toshima-ku, JP;

Yuki Iwata, Toshima-ku, JP;

Kenichi Kawabe, Toshima-ku, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 5/04 (2006.01); C07H 5/06 (2006.01); A01N 43/04 (2006.01); A61K 31/70 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides 4-isopropylphenyl glucitol compounds which have no tendency to accumulate in the body and which inhibit SGLT1 activity to suppress postprandial hyperglycemia (or impaired glucose tolerance) through suppression of glucose absorption in the small intestine, whereby the compounds, for example, can suppress the onset of diabetes and metabolic syndrome or can treat these diseases. A 4-isopropylphenyl glucitol compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof: wherein Rrepresents a hydrogen atom, etc., Rrepresents a methyl group, etc., Rrepresents a Calkyl group substituted with an amino group(s), etc., and Rrepresents a hydrogen atom, etc.


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