The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 18, 2013
Filed:
Aug. 30, 2012
Philippe Bussat, La Roche sur Foron, FR;
Bernard Lamy, Saint-Julien-en-Genevois, FR;
Edmund R. Marinelli, Tucson, AZ (US);
Sibylle Pochon, Troinex, CH;
BO Song, Princeton, NJ (US);
Rolf E. Swenson, Princeton, NJ (US);
Philippe Bussat, La Roche sur Foron, FR;
Bernard Lamy, Saint-Julien-en-Genevois, FR;
Edmund R. Marinelli, Tucson, AZ (US);
Sibylle Pochon, Troinex, CH;
Bo Song, Princeton, NJ (US);
Rolf E. Swenson, Princeton, NJ (US);
Bracco Imaging SpA, Milan, IT;
Abstract
Fibrin-binding peptides having high binding affinity and excellent physical characteristics compared to previously known fibrin-binding peptides are provided. These fibrin-binding peptides may be conjugated to a detectable label or a therapeutic agent and used to detect and facilitate treatment of pathological conditions associated with the presence of fibrin such as thrombic, angiogenic and neoplastic conditions. These peptides may be used in imaging processes such as MRI, ultrasound and nuclear medicine imaging (e.g. PET, scintigraphic imaging, etc.). The peptides may also be used therapeutically. The present invention also provides processes and methods for making and using such peptides and conjugates thereof.